Japan’s Nikkei share average rallied on Wednesday, gaining more than 1.5% in early trading, as renewed optimism over artificial intelligence (AI) demand boosted investor sentiment following gains on Wall Street.The benchmark Nikkei 225 climbed 1.56% to 65,074.56, while the broader Topix index advanced 1.03% to 4,050.65.US MarketsPowered ByAs on 21 Oct 2026, 01:30 AM ISTS&P 500 Top GainersEquifax176.54(11.33%)Hasbro109.52(11.20%)Moderna242.08(6.69%)3M171.37(5.78%)Gainers»S&P 500 Top LosersCoterra Energy32.56(-8.62%)General Motors77.09(-6.84%)DaVita175.35(-6.23%)Genuine Parts123.52(-5.12%)Losers»Read more: Global Market Today: Asian shares, US futures rise on AI-trade revival According to Reuters, sentiment around AI-related stocks improved after US equities rose overnight and SpaceX reported its first profit as a public company.